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Platform for Human Biomodels

The Basque Biomodel Platform for Human Research (BBioH) develops iPSC-derived human biomodels and offers services for human research and drug screening for internal and external users.

Our main objectives is to reproduce the principal stages of brain development, to model biological, biochemical and molecular hallmarks of the brain physiopathology and foster experimentation through humanized models. BBioH is a joint collaboration between Achucarro Basque Center for Neuroscience and Instituto Biofisika. BBioH strives to bridge the gap between the lab and the clinic.

BBioH has highly-qualified staff to operate the facility and assist users in identifying the best 2D and 3D cellular models to unravel their biological and biomedical questions.

This Platform has the support of the IKUR Strategy of the Department of Education of the Basque Government.

Microelectrode Array (MEAs) 3Brain BioCAM DupleX with 3D Module

Bizkaiko Foru Aldundiak finantzatu du proiektu hau, 2024ko Teknologia Transferentzia Programaren barruan
Este proyecto ha sido financiado por la Diputación Foral de Bizkaia dentro del Programa Transferencia Tecnológica 2024
This project has been funded by the Provincial Council of Bizkaia within the 2024 Technology Transfer Program

BioCAM DupleX is a high-resolution microelectrode array (also known as multielectrode array) platform for powerful in vitro functional imaging. It simultaneously records high-density electrophysiological data at 20 kHz and induce electrical neural network stimulation from 4,096 microelectrodes. This advanced platform works with both classical planar 2D cell culture as well as 3D HD-MEA technology. It is compatible with the latest generation of Khíron chips, which feature 4,096 µNeedle electrodes to penetrate structured brain tissues and obtain signals from inside your biological models such as slices, organoids, or spheroids.

Features:

  • REAL-TIME PROCESSING : Advanced FPGA control to denoise, filter and compress high-density data
    MAGNETIC SURFACES : Magnetic surfaces are present on the front of the BioCAM DupleX for easy setup with other equipment, such as perfusion holders
    TEMPERATURE CONTROL : Integrated heating and cooling system.
  • INTEGRATED STIMULATOR : 4 independently programmable current stimulator channels.
  • FAST LOCKING SYSTEM : A motorized solution to reliably lock and unlock CorePlateTM.
  • ROBUST EXTERNAL CASE : Crafted from aluminum to shield from electromagnetic and mechanical interference

Brain Organoids Summer Symposiums

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The Platform organizes the Brain Organoids Summer Symposium

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