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Jimena Baleriola Gómez de Pablos

Principal Investigator

Ikerbasque Research Associate

Jimena Baleriola Gómez de Pablos

Contact

Email:Jimena.Baleriola@achucarro.org

Tel.:(+34) 94 601 8496

Science Park of the UPV/EHU
Sede Building, 3rd floor, Barrio Sarriena, s/n
E-48940 Leioa Spain

About me

Dr. Baleriola got her PhD in 2008 after conducting her research at the Center for Biological Research Margarita Salas (CIB-CSIC, Madrid). To further her career in neuroscience research Dr. Baleriola joined the laboratory of Dr. Ulrich Hengst at the Taub Institute for Research on Alzheimer’s Disease and the Aging Brain, Columbia University (New York, USA) in 2010.

Her research projects aimed to unravel a possible role for intra-axonal protein synthesis in amyloid pathology, a central feature of AD. When she joined the Taub Institute there was no pre-existing evidence that local translation in axons could play a role in the adult central nervous system (CNS) in the context of neurodegenerative diseases. She defined a novel unexpected molecular pathway that mediates axon-to-soma spread of amyloid pathology that requires local mRNA translation in axons (Baleriola et al. 2014, Cell). Thanks to her postdoctoral work she was also one of the only twelve candidates that Columbia University nominated for the 2015 Blavatnik Awards for Young Scientists.

Publications

  1. Early deficits in an in vitro striatal microcircuit model carrying the Parkinson’s GBA-N370S mutation

    Do, Quyen B.; Noor, Humaira; Marquez-Gomez, Ricardo; Cramb, Kaitlyn M. L.; Ng, Bryan; Abbey, Ajantha; Ibarra-Aizpurua, Naroa; Caiazza, Maria Claudia; Sharifi, Parnaz; Lang, Charmaine; Beccano-Kelly, Dayne; Baleriola, Jimena; Bengoa-Vergniory, Nora; Wade-Martins, Richard
    npj Parkinson's Disease (Apr, 2024) DOI: 10.1038/s41531-024-00694-2
  2. CREB3L2-ATF4 heterodimerization defines a transcriptional hub of Alzheimer’s disease gene expression linked to neuropathology

    Gouveia Roque, Cláudio; Chung, Kyung Min; McCurdy, Ethan P.; Jagannathan, Radhika; Randolph, Lisa K.; Herline-Killian, Krystal; Baleriola, Jimena; Hengst, Ulrich
    Science Advances (Mar, 2023) DOI: 10.1126/sciadv.add2671
  3. Local Translation in Nervous System Pathologies

    Gamarra, María; de la Cruz, Aida; Blanco-Urrejola, Maite; Baleriola, Jimena
    Frontiers in Integrative Neuroscience (Jun, 2021) DOI: 10.3389/fnint.2021.689208