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Fabio Cavaliere

Senior Researcher

Director of the Biomodel Platform for Human Research (BBioH)

Fabio Cavaliere

Contact

Email:Fabio.Cavaliere@ehu.eus

Tel.:(+34) 94 601 8284

Science Park of the UPV/EHU
Sede Building, 3rd floor, Barrio Sarriena, s/n
E-48940 Leioa Spain

About me

Research interest
I study the mechanisms of cell regeneration and its relevance in CNS neurodegeneration and insult, especially in Parkinson’s disease and brain ischemia. The focus of the investigation is on the role of astrocytes as a mediator of neuronal metabolism and viability. The experimental models we use can range from in vitro cultures of rat adult neural stem cells (NSCs) to patient-derived pluripotent stem cells (iPS).

Experimental approaches

  • Brain organoids
  • Rat cell cultures (primary culture of post-natal SVZ-NSCs, organotypic)
  • Brain focal ischemia (intraluminal Middle Cerebral Artery Occlusion)
  • Human iPS-derived glia and neurons • Immunological assays (immunofluorescence, whole mount, Western blot)
  • Microfluidic
  • Metabolic and biochemistry assays
  • Molecular assays (PCR, PLA)

Collaborations
Universidad de La Laguna (Tenerife), HM CINAC (Madrid), CIMA (Pamplona), Biocruces Bizkaia (Barakaldo), Universitè de Bordeaux, Università di Roma Tor Vergata, University of Oxford, Universitäts klinikum Hamburg Eppendorf.