The neurobiology of insulin-like growth factor I: From neuroprotection to modulation of brain states
A novel formulation of the role in the brain of the evolutionary conserved IGF-I will hopefully help frame the actions of this prototypic neurotrophic signal and contribute to the design of new experimental approaches to understand its pleiotropy in the adult brain
The Laboratory of Neurobiology of Insulin Peptides published an Expert Review in Molecular Psychiatry on their expertise about IGF-I.
“After decades of research in the neurobiology of IGF-I, its role as a prototypical neurotrophic factor is undisputed. However, many of its actions in the adult brain indicate that this growth factor is not only involved in brain development or in the response to injury…”