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Juan Manuel Encinas Pérez

Principal Investigator

Ikerbasque

Juan Manuel Encinas Pérez

Research groups:

Contact

Email:JM.Encinas@achucarro.org

Tel.:(+34) 94 601 8138

Science Park of the UPV/EHU
Sede Building, 3rd floor, Barrio Sarriena, s/n
E-48940 Leioa Spain

0000-0002-0402-972X

About me

PhD Universidad Complutense de Madrid – Instituto Cajal (Spain), 2003

Our laboratory works on the study of the intrinsic properties of neural stem cells and neurogenesis in the adult hippocampus in normal conditions, aging and neurological disorders such as Epilepsy

Publications

  1. Biphasic changes in hippocampal granule cells after traumatic brain injury
    Danielewicz, Joanna; Llamosas, Nerea; Durá, Irene; de Souza, Danillo Barros; Rodrigues, Serafim; Encinas-Pérez, Juan Manuel; Mateos, Diego Martin
    Experimental Neurology (Aug, 2025) DOI: 10.1016/j.expneurol.2025.115281

  2. Purinergic receptor antagonism reduces interictal discharges and rescues cognitive function in a mouse model of temporal lobe epilepsy
    Espinosa, Nelson; Martín-Suárez, Soraya; Lara-Vasquez, Ariel; Montero, Trinidad; Muro-García, Teresa; Fernandez, German; Encinas-Pérez, Juan Manuel; Fuentealba, Pablo
    Frontiers in Neuroscience (Apr, 2025) DOI: 10.3389/fnins.2025.1513135

  3. Evolutionary convergence of sensory circuits in the pallium of amniotes
    Rueda-Alaña, Eneritz; Senovilla-Ganzo, Rodrigo; [...] De Pittà, Maurizio; García-Moreno, Fernando
    Science (Feb, 2025) DOI: 10.1126/science.adp3411

  4. HB-EGF activates EGFR to induce reactive neural stem cells in the mouse hippocampus after seizures
    Pastor-Alonso, Oier; Durá, Irene; Bernardo-Castro, Sara; Varea, Emilio; Muro-García, Teresa; Martín-Suárez, Soraya; Encinas-Pérez, Juan Manuel; Pineda, Jose Ramon
    Life Science Alliance (Sep, 2024) DOI: 10.26508/lsa.202201840

  5. BirthSeq, a new method to isolate and analyze dated cells in different vertebrates
    Rueda-Alaña, Eneritz; Grillo, Marco; Vázquez, Enrique; Salas, Sergio Marco; Senovilla-Ganzo, Rodrigo; Escobar, Laura; Quintas, Ana; Benguría, Alberto; Aransay, Ana María; Bengoa-Vergniory, Nora; Dopazo, Ana; Encinas, Juan Manuel; Nilsson, Mats; García-Moreno, Fernando
    Development (Jul, 2024) DOI: 10.1242/dev.202429

  6. Traumatic brain injury promotes neurogenesis at the cost of astrogliogenesis in the adult hippocampus of male mice
    Bielefeld, P.; Martirosyan, A.; [...] Holt, M. G.; Fitzsimons, C. P.
    Nature Communications (Jun, 2024) DOI: 10.1038/s41467-024-49299-6

  7. Generation of adult hippocampal neural stem cells occurs in the early postnatal dentate gyrus and depends on cyclin D2
    Pastor-Alonso, Oier; Syeda Zahra, Anum; Kaske, Bente; García-Moreno, Fernando; Tetzlaff, Felix; Bockelmann, Enno; Grunwald, Vanessa; Martín-Suárez, Soraya; Riecken, Kristoffer; Witte, Otto Wilhelm; Encinas, Juan Manuel; Urbach, Anja
    The EMBO Journal (Feb, 2024) DOI: 10.1038/s44318-023-00011-2

  8. Does the plasticity of neural stem cells and neurogenesis make them biosensors of disease and damage?
    Rodríguez-Bodero, Ane; Encinas-Pérez, Juan Manuel
    Frontiers in Neuroscience (Sep, 2022) DOI: 10.3389/fnins.2022.977209

  9. Damage-responsive neuro-glial clusters coordinate the recruitment of dormant neural stem cells in Drosophila
    Simões, Anabel R.; Neto, Marta; Alves, Carolina S.; Santos, Mariana B.; Fernández-Hernández, Ismael; Veiga-Fernandes, Henrique; Brea, David; Durá, Irene; Encinas, Juan M.; Rhiner, Christa
    Developmental Cell (Jul, 2022) DOI: 10.1016/j.devcel.2022.05.015

  10. Editorial: Neurogenesis and Gliogenesis as Potential Contributors to Neurorepair After Brain Damage
    Zepeda, A.; Encinas-Pérez, J.M.; Urbán, N.
    Frontiers in Neuroscience (Feb, 2022) DOI: 10.3389/fnins.2022.852729
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