This article shows the results of an amazing collaboration that led to successfully prepare fluorine-labelled nanoparticles (NPs) that are active inĀ 19F magnetic resonance imaging (19F MRI) by either conjugating four different fluorinated building blocks, shown in the 3D structure, to carboxyl-modified NPs or by direct grafting of PEG-fluorinated ligands. The research team obtainedĀ 19F MRI images of NPs accumulating in mice livers after intravenous injection.
This imaging study has been selected by the journalĀ ACS Applied Materials & InterfacesĀ to be the cover of the March Issue.
This work is the result of a fruitful collaboration between researchers and institutions in the Basque Country, like Ikerbasque, Instituto Biofisika (CSIC – UPV/EHU), CIC biomaGUNE and Achucarro Basque Center for Neuroscience.
https://doi.org/10.1021/acsami.1c01291