Want to tag the extracellular matrix (ECM) for live imaging?
22
Jul
2025
Federico N. Soria created an AAV vector, pAAV-CMVie-NcanGFP (a genetically encoded fluorescent tag for hyaluronan) that is available at Addgene.
Our AAV vector, pAAV-CMVie-NcanGFP is a genetically encoded fluorescent label for hyaluronan that can be used for live imaging of the ECM (ExtraCelullar Matrix) in mice in vivo.
It can be combined with structural (e.g. dendritic spines) and functional (e.g. calcium imaging) reporters to study brain cell physiology within the context of the ECM.
And the best part, it’s free!
It is available from Addgene https://www.addgene.org/235983/