Nanostructured scaffolds produced induce aligned migration of stem cells and accelerate their neuronal differentiation
The collaboration between different research groups of the UPV/EHU, and other institutions, among them ACHUCARRO, achieved a promising advance for future cell therapy: nanostructured scaffolds based on bioresorbable polymers and graphene derivatives that induce aligned migration and accelerate the neuronal differentiation of neural stem cells. This system has the potential to restore the connectivity of spatially oriented neural precursor cells and is a promising tool even in nerve tissue regeneration.
Con este proyecto, queremos demostrar que 1 de cada 3 casos de deterioro cognitivo se pueden evitar, manteniendo hábitos de vida activa y saludable
La fundación CITA Alzheimer lidera el proyecto de investigación CITA GO-ON, que tendrá una duración de 2 años, y va dirigido a la población adulta, en concreto a personas de entre 60 y 85 años. Y queremos contar con más de 1000 participantes. Durante ese tiempo, las personas participantes deberán realizarse algunas pruebas médicas, y se comprometerán a mantenerse activos física, mental y socialmente. También cuidarán su dieta, y tratarán de evitar los factores de riesgo cardiovascular.
Jan Tønnesen and Federico Soria join an international consortium, headed by Professor Miquel Vila (Autonomous University of Barcelona), in a research project awarded 10 million dollars from the Aligning Science Across Parkinson's (ASAP) initiative
Parkinson's disease is a degenerative neurological disorder that primarily affects the brain's motor system and is symptomatically characterized by tremor, rigidity, and slowing of movements. It is the second most common neurodegenerative disorder after Alzheimer's disease. The underlying cause is unknown, though both inherited genetic and environmental risk factors have been identified.
Fruit of the altruistic work of an interdisciplinary group of researchers from ACHUCARRO and the department of Genetics of the UPV/EHU during the pandemic
An interdisciplinary group of researchers, among them our colleague José Ramón Pineda Martí from ACHUCARRO, led by José Ramón Bilbao and Nora Fernandez-Jimenez from the department of Genetics of the UPV/EHU developed an altruistic work during the pandemic to help in the analysis of PCR data. The result is ShinyCurves, an on-line automated web application to analyze multisource qPCR amplification data from multi-plate and multi-platform formats.
Human iPSC-derived astrocytes transplanted into the mouse brain undergo morphological changes in response to amyloid-β plaques
A research team at ACHUCARRO, together with scientists at VIB-KU Leuven (Belgium) and Icahn School of Medicine at Mount Sinai (US), collaborate in this work published in Molecular Neurodegeneration
A new method developed by a group of scientists led by Ikerbasque researcher Amaia Arranz pioneers the transplantation of human astrocytes into mice brains. To study the effects of Alzheimer's disease in a more natural environment, these scientists transplanted human astrocytes into mouse brains containing amyloid plaques, one of the main hallmarks of Alzheimer's disease.