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Biomarkers Platform | SIngle MOlecule Array

ULTRA SENSITIVE DIGITAL IMMUNOASSAYS

Quanterix SIMOA HD-X

Our Quanterix SIMOA HD-X analyzer is a fully automated platform based on Single Molecule Array (SIMOA) technology, a digital version of ELISA. Individual immunocomplexes formed on paramagnetic beads are isolated and sealed in thousands of femtoliter-sized microwells on SIMOA discs, enabling digital counting of single protein molecules.

This digital detection format provides up to 1000-fold higher sensitivity than conventional immunoassays, enabling precise quantification of extremely low-abundance protein biomarkers and supporting precision medicine applications.

  • Throughput: 3 plates per 8-hour shift (~300 datapoints/day)
  • Fully automated workflow (plate or tube format)
  • Total assay time < 2.5 h per 96‑well plate
  • Hands‑on/startup time < 20 min
  • Sample input: 96‑well plate or tubes
  • Sample volume: 1 µL–100 µL
  • Multiplexing: up to 4‑plex
Benefits
  • Ultra-sensitivity: detect proteins at fg/mL levels
  • Automation: highly reproducible, sample-to-answer workflow
  • Multiplexing: up to 4 biomarkers in a single sample
  • Flexibility for high-throughput or fast‑turnaround workflows
  • Efficiency: stable calibration and consistent assay conditions
  • Broad menu: >80 available assays + homebrew capability
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