Joint application for a Postdoctoral fellowship in Neuroimaging and biomarkers of inflammation

Summary Information

Category: Postdoctoral fellowship, Marie Skłodowska-Curie actions 2019, Individual Fellowship
Type of Contract: 24 months
Working Hours: 40 hours/week
Salary: Established by the MSCA actions
Location: Leioa, Spain
Deadline: July 14th 2019
Job Starting Date: Expected by the first quarter of 2020.
How to apply: Send an updated CV, a motivation letter and the contact details of 2 referees to indicating in the subject of the message: MCSA-IF 2019

Description of the host laboratory

The existence of in vivo neuroimaging methods such as positron emission tomography, single photon emission computed tomography, magnetic resonance imaging, computed tomography, optical and ultrasound imaging have been indispensable for early diagnosis, in monitoring disease progression and therapy of a wide range of brain diseases such as stroke and brain hemorrhage. The inflammatory response is a major factor in neurovascular pathophysiology and contributes to secondary neuronal damage in both acute and chronic stages of the ischemic injury. Recent work in experimental cerebral ischemia has demonstrated the involvement of neurotransmitter signalling in the modulation of neuroinflammation, providing evidence of the role of neurotransmission receptors as a promising inflammatory biomarkers in neurovascular research. Therefore, our main goal is to evaluate the therapeutic potential and diagnostic perspectives of cannabinoid, cholinergic, purinergic and glutamatergic receptors and transporters in experimental stroke using non-invasive molecular imaging technologies. Besides, we are also interested in to visualize and quantify biological processes (i) during acute phase of ischemic stroke and subarachnoid hemorrhage as metalloproteinase activity, oxidative stress, brain perfusion and cell death at the cellular/molecular level and (ii) affecting sub-acute phases as angiogenesis and brain function recovery. Further applications are envisaged and could be explored within the frame of the MSCA programme.

This research will foster the emergence of new therapeutic strategies that may recognize and modulate the inflammatory response after neurovascular pathologies. Finally, the knowledge derived from this research could be easily applied to the clinics and to other neurologic and neurodegenerative diseases.

The Neuroimaging and biomarkers of inflammation Lab is looking for a highly-motivated experienced researcher of any nationality interested in applying for the Marie Skłodowska-Curie Actions Individual Fellowship call (H2020-MSCA-IF-2019), who wishes to work in the field of neuroimaging applied to solve and study neuroinflammation in cerebrovascular diseases.

Qualifications and Experience

A competitive research CV, with a PhD degree in neuroscience or related scientific field.

Fluency in English is an asset, and good communication skills will be very positively evaluated.

About Achucarro

Achucarro Basque Center for Neuroscience (ACHUCARRO) is a Basque Excellence Research Center (BERC) created by the Basque Government in 2012. Since 2017 this center is located in a new building in the Science Park of in Leioa, the main campus of the public University of the Basque Country (UPV/EHU), that provides cutting-edge facilities. The center has been awarded by the European Commission with the HR Excellence in Research to his commitment with the European charter for researchers and the code of conduct for the recruitment of researchers. It hosts 35 senior and associate researchers developing research lines in the field of neuron-glia interactions in the normal and pathological brain, 10 postdocs, more than 10 technician/management personnel and provides training opportunities to about 30 PhD students. In the center, they have carried out many projects funded by the Basque Government, Spanish Government, European Union, etc. Since 2015, Achucarro as a whole has more than 200 scientific publications in prestigious international journals which have received nearly 4.000 cites. It is at the forefront in the field of neurosciences providing a multidisciplinary environment where several areas of expertise (medicine, biology, biochemistry and pharmacy) meet, creating a unique and internationally-recognized research center.

Achucarro commits to the principles laid down in the European Commission's Recommendation (March 11, 2005) for the European Charter for Researchers (The Code of Conduct for the Recruitment of Researchers).