{"version":"1.0","provider_name":"Achucarro Basque Center for Neuroscience","provider_url":"https:\/\/www.achucarro.org\/eu\/","title":"Effect of APOE3 and APOE4 hAstrocytes in AD chimeric mice - Achucarro Basque Center for Neuroscience","type":"rich","width":600,"height":338,"html":"<blockquote class=\"wp-embedded-content\" data-secret=\"ilgdbMN7uU\"><a href=\"https:\/\/www.achucarro.org\/eu\/mintegia\/2026-06-marta-miron\/\">Effect of APOE3 and APOE4 hAstrocytes in AD chimeric mice<\/a><\/blockquote><iframe sandbox=\"allow-scripts\" security=\"restricted\" src=\"https:\/\/www.achucarro.org\/eu\/mintegia\/2026-06-marta-miron\/embed\/#?secret=ilgdbMN7uU\" width=\"600\" height=\"338\" title=\"&#8220;Effect of APOE3 and APOE4 hAstrocytes in AD chimeric mice&#8221; &#8212; Achucarro Basque Center for Neuroscience\" data-secret=\"ilgdbMN7uU\" frameborder=\"0\" marginwidth=\"0\" marginheight=\"0\" scrolling=\"no\" class=\"wp-embedded-content\"><\/iframe><script>\n\/*! This file is auto-generated *\/\n!function(d,l){\"use strict\";l.querySelector&&d.addEventListener&&\"undefined\"!=typeof URL&&(d.wp=d.wp||{},d.wp.receiveEmbedMessage||(d.wp.receiveEmbedMessage=function(e){var t=e.data;if((t||t.secret||t.message||t.value)&&!\/[^a-zA-Z0-9]\/.test(t.secret)){for(var s,r,n,a=l.querySelectorAll('iframe[data-secret=\"'+t.secret+'\"]'),o=l.querySelectorAll('blockquote[data-secret=\"'+t.secret+'\"]'),c=new RegExp(\"^https?:$\",\"i\"),i=0;i<o.length;i++)o[i].style.display=\"none\";for(i=0;i<a.length;i++)s=a[i],e.source===s.contentWindow&&(s.removeAttribute(\"style\"),\"height\"===t.message?(1e3<(r=parseInt(t.value,10))?r=1e3:~~r<200&&(r=200),s.height=r):\"link\"===t.message&&(r=new URL(s.getAttribute(\"src\")),n=new URL(t.value),c.test(n.protocol))&&n.host===r.host&&l.activeElement===s&&(d.top.location.href=t.value))}},d.addEventListener(\"message\",d.wp.receiveEmbedMessage,!1),l.addEventListener(\"DOMContentLoaded\",function(){for(var e,t,s=l.querySelectorAll(\"iframe.wp-embedded-content\"),r=0;r<s.length;r++)(t=(e=s[r]).getAttribute(\"data-secret\"))||(t=Math.random().toString(36).substring(2,12),e.src+=\"#?secret=\"+t,e.setAttribute(\"data-secret\",t)),e.contentWindow.postMessage({message:\"ready\",secret:t},\"*\")},!1)))}(window,document);\n\/\/# sourceURL=https:\/\/www.achucarro.org\/wp-includes\/js\/wp-embed.min.js\n<\/script>\n","description":"Astrocytes and apolipoprotein E (APOE) are both strongly implicated in the pathogenesis and progression of Alzheimer\u2019s disease (AD), yet the impact of astrocytes carrying different APOE variants on key AD hallmarks remains largely unknown. To explore this in a human-relevant context, we generated a chimeric model of AD by transplanting isogenic APOE3 or APOE4 human [&hellip;]"}