1.0Achucarro Basque Center for Neurosciencehttps://www.achucarro.org/eu/rich600338<blockquote class="wp-embedded-content" data-secret="35PMNt3Rjm"><a href="https://www.achucarro.org/eu/mintegia/2024-04-paloma-mata/">Role of the P2X4 receptor in MS pathology</a></blockquote><iframe sandbox="allow-scripts" security="restricted" src="https://www.achucarro.org/eu/mintegia/2024-04-paloma-mata/embed/#?secret=35PMNt3Rjm" width="600" height="338" title="“Role of the P2X4 receptor in MS pathology” — Achucarro Basque Center for Neuroscience" data-secret="35PMNt3Rjm" frameborder="0" marginwidth="0" marginheight="0" scrolling="no" class="wp-embedded-content"></iframe><script> /*! This file is auto-generated */ !function(d,l){"use strict";l.querySelector&&d.addEventListener&&"undefined"!=typeof URL&&(d.wp=d.wp||{},d.wp.receiveEmbedMessage||(d.wp.receiveEmbedMessage=function(e){var t=e.data;if((t||t.secret||t.message||t.value)&&!/[^a-zA-Z0-9]/.test(t.secret)){for(var s,r,n,a=l.querySelectorAll('iframe[data-secret="'+t.secret+'"]'),o=l.querySelectorAll('blockquote[data-secret="'+t.secret+'"]'),c=new RegExp("^https?:$","i"),i=0;i<o.length;i++)o[i].style.display="none";for(i=0;i<a.length;i++)s=a[i],e.source===s.contentWindow&&(s.removeAttribute("style"),"height"===t.message?(1e3<(r=parseInt(t.value,10))?r=1e3:~~r<200&&(r=200),s.height=r):"link"===t.message&&(r=new URL(s.getAttribute("src")),n=new URL(t.value),c.test(n.protocol))&&n.host===r.host&&l.activeElement===s&&(d.top.location.href=t.value))}},d.addEventListener("message",d.wp.receiveEmbedMessage,!1),l.addEventListener("DOMContentLoaded",function(){for(var e,t,s=l.querySelectorAll("iframe.wp-embedded-content"),r=0;r<s.length;r++)(t=(e=s[r]).getAttribute("data-secret"))||(t=Math.random().toString(36).substring(2,12),e.src+="#?secret="+t,e.setAttribute("data-secret",t)),e.contentWindow.postMessage({message:"ready",secret:t},"*")},!1)))}(window,document); //# sourceURL=https://www.achucarro.org/wp-includes/js/wp-embed.min.js </script> Microglia play many beneficial roles in multiple sclerosis (MS) including the removal of neurotoxins and damaged myelin as well as by fostering repair. We previously found that the P2X4 positive allosteric modulator ivermectin increases myelin phagocytosis, promotes remyelination and improves symptoms recovery in experimental autoimmune encephalomyelitis (EAE). To define accurately the selectivity of the pharmacological […]